Generally I do this with a River and some mid (depends on what I feel; Roc, Fuse, or Ridge), however, today I was throwing strictly a Buzzz SS and Discmania's P2. I did have a Flow with me but I only used it on one hole and I missed the putt, so the end result would have been the same if I had teed off with the Buzzz SS and then had a decent approach.
I finished today -4 under the par for the 11 holes I played. It was a nice day, close to my all time low (12 hole course where that hole I skipped could swing one throw lower but sometimes 3 over).
Most courses where I play only 2 discs I can get away with it. Where I play most of my leagues and tournaments, however, usually require enough different shots where I feel more confident if I have the whole bag.