Pick a midrange workhorse and go from there. the usual suspects are: Roc & Buzzz. I'm not going to go into the old fight but I will say they are different and work to different styles of play.
Roc is a bit shorter but more overstable. it is better in base plastic and can be used as a single mold in different stages of wear and in different weights. most Roc throwers tend to have a traditional "Fairway" driver in their bag.
Buzzzes are longer and straight. they work best in premium plastic (specifically Z). Buzzzes also tend to need the complement of other discs (usually something like a Comet and Hornet). more advanced players can really work the buzzz by itself but I need the help from other discs. Buzzz throwers can usually get away with just the Buzzz and a longer control driver like a PD or OLF and not use a traditional "Fairway".
after you've selected your mid (which IMHO is the backbone of your setup), you can pick your main driver as mentioned above. and then based on what you throw as a main driver you can then pick a distance driver if necessary. I'm not so well steeped on the double digit speed drivers but my 2¢ is that they are better used if you can throw a Teebird consistently 350+.
depending on your style you can pick a OS driver. I still subscribe to the Type I vs Type II OS disc theory. a Type I is like the FB or xXx, something ridiculously OS that fades immediately out of your hand. these discs don't go far and are better for trick shots etc. the Type II is like the Pred or Trident (the good ones). they go straight and then fade hard. they are good distance wind fighters and can still do the trick shots like the type I's but not as well. your "utility" disc really depends on your approach to the game and your main driver selection.
last but not least are putters. you do need a good driving putter but sometimes a different mold is better for putting depending on your putting style. I also like lid type putters for touch approaches.
I'll use my setup as an example.
Wizard | Polecat | Hornet | Buzzz | Comet | xXx | Avenger
I putt and drive with Wizards but I like the Polecat for weird touch shots.
I use the Buzzz b/w 280 & 350 but I'm not great at manipulating it. so I use the Comet and Hornet for the other situations that don't require a laser straight shot.
I use the Avenger for anything over 350. I use X's for big turnovers and rolling and I use Z's for stable driving and long FH's (which I suck at).
I love the xXx for OH and FH rollers etc. there are also a few holes on the courses I play that need that hard BH fade.